Fwd: New materials request (SOPC and cholesterol)

Elizabeth Ann Hager-Barnard lizhb at stanford.edu
Tue Apr 14 20:27:58 PDT 2009

Dear Members of the SpecMat Committee,

If you have any questions about the request I submitted last week,  
please let me know.  I would be glad to provide additional  
information.  In case you did not receive my request I have included  
the original e-mail below.

Thank you,

Elizabeth Hager-Barnard
Ph.D. candidate
Melosh Group
Dept. of Mat. Sci. and Eng.

Begin forwarded message:

> From: Elizabeth Ann Hager-Barnard <lizhb at stanford.edu>
> Date: April 7, 2009 12:07:42 PM PDT
> To: specmat at snf.stanford.edu
> Subject: New materials request
> To Whom It May Concern:
> My name is Elizabeth Hager-Barnard and I am a 4th year Ph.D. student  
> in Nick Melosh’s group (Materials Science and Engineering).  I have  
> worked in SNF previously and I am now beginning a collaboration with  
> Fatih Sarioglu from Prof. Solgaard’s group.  Fatih has developed new  
> AFM techniques and my group plans to help him apply his techniques  
> to new systems.  We will be using the Agilent AFM in SNF.
> The purpose of this e-mail is to request permission to bring new  
> materials into SNF to use with the AFM.  Specifically, I would like  
> to bring synthetic lipid molecules and cholesterol into SNF.  These  
> materials, as confirmed by the attached MSDS files, are non- 
> hazardous.  These materials will only be used on the AFM.  They will  
> not contact any other equipment in the lab.  We will not do any  
> processing of these materials in SNF.  Furthermore, we will neither  
> store nor dispose of these materials in SNF.
> In the remainder of this e-mail I have responded to the questions  
> outlined in the SNF webpage, “Procedures for Bringing in New  
> Chemicals & Materials”.  If you have any further questions regarding  
> this request please let me know.
> Thank you for your time,
> Elizabeth Hager-Barnard
> Your contact information:
>             Name:                     Elizabeth Hager-Barnard
> Coral login:      	lizhb
> E-mail:                   	lizhb at stanford.edu
> Phone number:      	650-796-9302
> PI:                           	Nick Melosh (Materials Science and  
> Engineering)
> The chemical or material:
>             Synthetic lipid molecules: for example, SOPC
> SOPC   (18:0-18:1 PC,  C44H86NO8P)
>      2 alternative naming schemes:
>           1-stearoyl-2-oleyl-sn-glycero-3-phosphocholine      OR
>           1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3- 
> phosphocholine
> Cholesterol: cholesterol derived from ovine wool
> Saline solution: for example, 2% NaCl in water
> Note: lipid molecules are amphiphilic molecules with hydrophilic  
> headgroups and hydrophobic tails.  The lipid molecules we would use  
> are synthetic and non-hazardous.
> MSDS sheets for SOPC and cholesterol are attached to this e-mail.   
> All the synthetic lipid molecules we would use have similar MSDS and  
> are all non-hazardous.
> Vendor:          		    Avanti Polar Lipids
>                                     700 Industrial Park Drive
>                                     Alabaster, Alabama 35007-9105
>                                     www.avantilipids.com
> (800) 227-0651
> We will not store our materials in SNF.  Synthetic lipid molecules  
> and cholesterol derived from ovine wool are not hazardous (they do  
> not have a hazard class).
> Reason for request:
>             We would like to bring these materials into SNF as part  
> of our colloboration with the Solgaard group.  We have used these  
> materials many times in a different AFM, but in order to use the new  
> techniques developed by the Solgaard group, we need to use them with  
> the SNF AFM.  No other approved SNF materials are similar to the  
> ones we are requesting.  Our materials are not hazardous.
> Process Flow:
>             We will only use our materials on the AFM.  We will not  
> do any processing of our materials in SNF.  We will simply place our  
> materials onto the AFM stage.
> Amount and form:
>             Our materials will not be in powder form when we bring  
> them into SNF.  In our lab in McCullough, we will form a sheet of  
> lipids and cholesterol on a glass slide, and put the glass slide in  
> a beaker with saline solution (NaCl in water).  I expect that the  
> glass slide will be about 25mm in diameter and the slide will be  
> submerged in approximately 5ml of saline solution.  We will cover  
> the beaker when bringing it into SNF.  While in SNF we will not do  
> any processing of our material, except to possibly pipette  
> additional saline solution over the glass slide if a significant  
> fraction of the solution evaporates.
> Storage:
>              We will not store our materials at SNF.
> Disposal:
> We will not dispose our materials in SNF.  We will remove our  
> materials from SNF and dispose of them in our own lab in  
> McCullough.  We will clean the AFM head when we are finished.

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