Fwd: New materials request (SOPC and cholesterol)
Mary Tang
mtang at stanford.edu
Tue Apr 21 15:54:41 PDT 2009
Hi all --
Elizabeth just came by to talk about her request. From a general
chemical safety/contamination standpoint, this should be OK. I'll have
to defer to Ed for tools specifics, but there are two possible
concerns. First, does the Agilent AFM have a wet cell? Second, the
solution contains significant amounts of sodium, so I was not sure if
there were cross-contamination concerns on this system.
Ed?
Mary
Elizabeth Ann Hager-Barnard wrote:
> Dear Members of the SpecMat Committee,
>
> If you have any questions about the request I submitted last week,
> please let me know. I would be glad to provide additional
> information. In case you did not receive my request I have included
> the original e-mail below.
>
> Thank you,
>
> Elizabeth Hager-Barnard
> Ph.D. candidate
> Melosh Group
> Dept. of Mat. Sci. and Eng.
> (650)796-9302
>
>
> Begin forwarded message:
>
>> *From: * Elizabeth Ann Hager-Barnard <lizhb at stanford.edu
>> <mailto:lizhb at stanford.edu>>
>> *Date: * April 7, 2009 12:07:42 PM PDT
>> *To: * specmat at snf.stanford.edu <mailto:specmat at snf.stanford.edu>
>> *Subject: * *New materials request*
>>
>> To Whom It May Concern:
>>
>> My name is Elizabeth Hager-Barnard and I am a 4 ^ th year Ph.D.
>> student in Nick Melosh’s group (Materials Science and Engineering).
>> I have worked in SNF previously and I am now beginning a
>> collaboration with Fatih Sarioglu from Prof. Solgaard’s group.
>> Fatih has developed new AFM techniques and my group plans to help him
>> apply his techniques to new systems. We will be using the Agilent
>> AFM in SNF.
>>
>> The purpose of this e-mail is to request permission to bring new
>> materials into SNF to use with the AFM. Specifically, I would like
>> to bring synthetic lipid molecules and cholesterol into SNF. These
>> materials, as confirmed by the attached MSDS files, are
>> non-hazardous. These materials will only be used on the AFM. They
>> will not contact any other equipment in the lab. We will not do any
>> processing of these materials in SNF. Furthermore, we will neither
>> store nor dispose of these materials in SNF.
>>
>> In the remainder of this e-mail I have responded to the questions
>> outlined in the SNF webpage, “ Procedures for Bringing in New
>> Chemicals & Materials”. If you have any further questions regarding
>> this request please let me know.
>>
>>
>>
>> Thank you for your time,
>>
>> Elizabeth Hager-Barnard
>>
>>
>>
>>
>>
>>
>> Your contact information:
>>
>> Name: Elizabeth Hager-Barnard
>> Coral login: lizhb
>> E-mail: lizhb at stanford.edu
>> <mailto:lizhb at stanford.edu>
>> Phone number: 650-796-9302
>> PI: Nick Melosh (Materials Science and
>> Engineering)
>>
>>
>> The chemical or material:
>>
>> Synthetic lipid molecules : for example, SOPC
>>
>> SOPC (18:0-18:1 PC, C _ 44 H _ 86 NO _ 8 P)
>> 2 alternative naming schemes:
>> 1- stearoyl -2-oleyl-sn-glycero-3-phosphocholine OR
>>
>> 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine
>>
>> Cholesterol : cholesterol derived from ovine wool
>>
>> Saline solution : for example, 2% NaCl in water
>>
>>
>>
>> Note: lipid molecules are amphiphilic molecules with hydrophilic
>> headgroups and hydrophobic tails. The lipid molecules we would use
>> are synthetic and non-hazardous.
>>
>> MSDS sheets for SOPC and cholesterol are attached to this e-mail.
>> All the synthetic lipid molecules we would use have similar MSDS and
>> are all non-hazardous.
>>
>>
>>
>> Vendor: Avanti Polar Lipids
>>
>> 700 Industrial Park Drive
>>
>> Alabaster, Alabama 35007-9105
>>
>> www.avantilipids.com
>> <http://www.avantilipids.com>
>>
>> (800) 227-0651
>>
>>
>>
>> We will not store our materials in SNF. Synthetic lipid molecules
>> and cholesterol derived from ovine wool are not hazardous (they do
>> not have a hazard class).
>>
>> Reason for request:
>> We would like to bring these materials into SNF as part
>> of our colloboration with the Solgaard group. We have used these
>> materials many times in a different AFM, but in order to use the new
>> techniques developed by the Solgaard group, we need to use them with
>> the SNF AFM. No other approved SNF materials are similar to the
>> ones we are requesting. Our materials are not hazardous.
>>
>>
>>
>> Process Flow:
>>
>> We will only use our materials on the AFM. We will not
>> do any processing of our materials in SNF. We will simply place our
>> materials onto the AFM stage.
>>
>>
>>
>> Amount and form:
>> Our materials will not be in powder form when we bring
>> them into SNF. In our lab in McCullough, w e will form a sheet of
>> lipids and cholesterol on a glass slide, and put the glass slide in a
>> beaker with saline solution (NaCl in water). I expect that the
>> glass slide will be about 25mm in diameter and t he slide will be
>> submerged in approximately 5ml of saline solution. We will cover
>> the beaker when bringing it into SNF. While in SNF we will not do
>> any processing of our material, except to possibly pipette additional
>> saline solution over the glass slide if a significant fraction of the
>> solution evaporates.
>>
>>
>>
>> Storage:
>> We will not store our materials at SNF.
>>
>> Disposal :
>>
>> We will not dispose our materials in SNF. We will remove our
>> materials from SNF and dispose of them in our own lab in McCullough.
>> We will clean the AFM head when we are finished.
>>
>>
>>
> =
> ------------------------------------------------------------------------
>
>>
>>
>
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>
>>
>>
>
--
Mary X. Tang, Ph.D.
Stanford Nanofabrication Facility
CIS Room 136, Mail Code 4070
Stanford, CA 94305
(650)723-9980
mtang at stanford.edu
http://snf.stanford.edu
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