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Xylenes

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MSDS Number: X2000 * * * * * Effective Date: 02/16/06 * * * * * Supercedes: 04/01/03


XYLENES


1. Product Identification

Synonyms: Dimethyl benzene, xylol, methyltoluene
CAS No.: 1330-20-7
Molecular Weight: 106.17
Chemical Formula: C6H4(CH3)2
Product Codes:
J.T. Baker: 5377, 5813, 9483, 9489, 9490, 9493, 9494, 9499, 9516, X516
Mallinckrodt: 8664, 8668, 8671, 8672, 8802, V052

2. Composition/Information on Ingredients

 

  Ingredient                                CAS No         Percent        Hazardous                                  
  ---------------------------------------   ------------   ------------   ---------   
 
  m-Xylene                                  108-38-3         40 - 65%        Yes                                                                   
  o-Xylene                                  95-47-6          15 - 20%        Yes                                                                   
  p-Xylene                                  106-42-3           < 20%         Yes                                                                  
  Ethyl Benzene                             100-41-4         15 - 25%        Yes                                                                   
 

3. Hazards Identification

Emergency Overview
--------------------------
DANGER! HARMFUL OR FATAL IF SWALLOWED. VAPOR HARMFUL. AFFECTS CENTRAL NERVOUS SYSTEM. CAUSES SEVERE EYE IRRITATION. CAUSES IRRITATION TO SKIN AND RESPIRATORY TRACT. MAY BE HARMFUL IF ABSORBED THROUGH SKIN. CHRONIC EXPOSURE CAN CAUSE ADVERSE LIVER, KIDNEY, AND BLOOD EFFECTS. FLAMMABLE LIQUID AND VAPOR.

SAF-T-DATA(tm) Ratings (Provided here for your convenience)
-----------------------------------------------------------------------------------------------------------
Health Rating: 2 - Moderate (Life)
Flammability Rating: 2 - Moderate
Reactivity Rating: 1 - Slight
Contact Rating: 3 - Severe
Lab Protective Equip: GOGGLES; LAB COAT; VENT HOOD; PROPER GLOVES; CLASS B EXTINGUISHER
Storage Color Code: Red (Flammable)
-----------------------------------------------------------------------------------------------------------

Potential Health Effects
----------------------------------

Inhalation:
Inhalation of vapors may be irritating to the nose and throat. Inhalation of high concentrations may result in nausea, vomiting, headache, ringing in the ears, and severe breathing difficulties which may be delayed in onset. Substernal pain, cough, and hoarseness are also reported. High vapor concentrations are anesthetic and central nervous system depressants.
Ingestion:
Ingestion causes burning sensation in mouth and stomach, nausea, vomiting and salivation. Minute amounts aspirated into the lungs can produce a severe hemorrhagic pneumonitis with severe pulmonary injury or death.
Skin Contact:
Skin contact results in loss of natural oils and often results in a characteristic dermatitis. May be absorbed through the skin.
Eye Contact:
Vapors cause eye irritation. Splashes cause severe irritation, possible corneal burns and eye damage.
Chronic Exposure:
Chronic inhalation can cause headache, loss of appetite, nervousness and pale skin. Repeated or prolonged skin contact may cause a skin rash. Repeated exposure of the eyes to high concentrations of vapor may cause reversible eye damage. Repeated exposure can damage bone marrow, causing low blood cell count. May damage the liver and kidneys.
Aggravation of Pre-existing Conditions:
Persons with pre-existing skin disorders or eye problems, or impaired liver, kidney, blood, or respiratory function may be more susceptible to the effects of the substance.

4. First Aid Measures

Inhalation:
Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Call a physician immediately.
Ingestion:
Aspiration hazard. If swallowed, vomiting may occur spontaneously, but DO NOT INDUCE. If vomiting occurs, keep head below hips to prevent aspiration into lungs. Never give anything by mouth to an unconscious person. Call a physician immediately.
Skin Contact:
Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical attention. Wash clothing before reuse. Thoroughly clean shoes before reuse.
Eye Contact:
Immediately flush eyes with plenty of water for at least 15 minutes, lifting lower and upper eyelids occasionally. Get medical attention immediately.

5. Fire Fighting Measures

Fire:
Flash point: 29C (84F) CC
Autoignition temperature: 464C (867F)
Flammable limits in air % by volume:
lel: 1.0; uel: 7.0
Explosion:
Above flash point, vapor-air mixtures are explosive within flammable limits noted above. Contact with strong oxidizers may cause fire. Sealed containers may rupture when heated. Sensitive to static discharge.
Fire Extinguishing Media:
Dry chemical, foam or carbon dioxide. Water spray may be used to keep fire exposed containers cool, dilute spills to nonflammable mixtures, protect personnel attempting to stop leak and disperse vapors.
Special Information:
In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full facepiece operated in the pressure demand or other positive pressure mode. Vapors can flow along surfaces to distant ignition source and flash back.

6. Accidental Release Measures

Ventilate area of leak or spill. Remove all sources of ignition. Wear appropriate personal protective equipment as specified in Section 8. Isolate hazard area. Keep unnecessary and unprotected personnel from entering. Contain and recover liquid when possible. Use non-sparking tools and equipment. Collect liquid in an appropriate container or absorb with an inert material (e. g., vermiculite, dry sand, earth), and place in a chemical waste container. Do not use combustible materials, such as saw dust. Do not flush to sewer! If a leak or spill has not ignited, use water spray to disperse the vapors, to protect personnel attempting to stop leak, and to flush spills away from exposures. US Regulations (CERCLA) require reporting spills and releases to soil, water and air in excess of reportable quantities. The toll free number for the US Coast Guard National Response Center is (800) 424-8802.


J. T. Baker SOLUSORB� solvent adsorbent is recommended for spills of this product.

7. Handling and Storage

Protect against physical damage. Store in a cool, dry well-ventilated location, away from any area where the fire hazard may be acute. Outside or detached storage is preferred. Separate from incompatibles. Containers should be bonded and grounded for transfers to avoid static sparks. Storage and use areas should be No Smoking areas. Use non-sparking type tools and equipment, including explosion proof ventilation. Containers of this material may be hazardous when empty since they retain product residues (vapors, liquid); observe all warnings and precautions listed for the product. Do Not attempt to clean empty containers since residue is difficult to remove. Do not pressurize, cut, weld, braze, solder, drill, grind or expose such containers to heat, sparks, flame, static electricity or other sources of ignition: they may explode and cause injury or death.

8. Exposure Controls/Personal Protection

Airborne Exposure Limits:
-OSHA Permissible Exposure Limit (PEL):
100 ppm (TWA) xylene
100 ppm (TWA) ethylbenzene
-ACGIH Threshold Limit Value (TLV):
xylene: 100 ppm (TWA) 150 ppm (STEL), A4 - Not classifiable as a human carcinogen.
ethyl benzene: 100 ppm (TWA) 125 ppm (STEL), A3 - Confirmed Animal Carcinogen with Unknown Relevance to Humans.
Ventilation System:
A system of local and/or general exhaust is recommended to keep employee exposures below the Airborne Exposure Limits. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area. Please refer to the ACGIH document, Industrial Ventilation, A Manual of Recommended Practices, most recent edition, for details. Use explosion-proof equipment.
Personal Respirators (NIOSH Approved):
If the exposure limit is exceeded and engineering controls are not feasible, a half-face organic vapor respirator may be worn for up to ten times the exposure limit, or the maximum use concentration specified by the appropriate regulatory agency or respirator supplier, whichever is lowest. A full-face piece organic vapor respirator may be worn up to 50 times the exposure limit, or the maximum use concentration specified by the appropriate regulatory agency or respirator supplier, whichever is lowest. For emergencies or instances where the exposure levels are not known, use a full-face piece positive-pressure, air-supplied respirator. WARNING: Air-purifying respirators do not protect workers in oxygen-deficient atmospheres. Where respirators are required, you must have a written program covering the basic requirements in the OSHA respirator standard. These include training, fit testing, medical approval, cleaning, maintenance, cartridge change schedules, etc. See 29CFR1910.134 for details.
Skin Protection:
Wear impervious protective clothing, including boots, gloves, lab coat, apron or coveralls, as appropriate, to prevent skin contact.
Eye Protection:
Use chemical safety goggles and/or a full face shield where splashing is possible. Maintain eye wash fountain and quick-drench facilities in work area.

9. Physical and Chemical Properties

The following physical data is for xylene.
Appearance:
Clear, colorless liquid.
Odor:
Characteristic odor.
Solubility:
Insoluble in water.
Specific Gravity:
0.86 @ 20C/4C
pH:
Not applicable.
% Volatiles by volume @ 21C (70F):
100
Boiling Point:
137 - 140C (279 - 284F)
Melting Point:
-25C (-13F)
Vapor Density (Air=1):
3.7
Vapor Pressure (mm Hg):
8 @ 20C (68F)
Evaporation Rate (BuAc=1):
0.7

10. Stability and Reactivity

Stability:
Stable under ordinary conditions of use and storage.
Hazardous Decomposition Products:
Involvement in a fire causes formation of carbon monoxide and unidentified organic components.
Hazardous Polymerization:
Will not occur.
Incompatibilities:
Strong oxidizing agents and strong acids.
Conditions to Avoid:
Heat, flames, ignition sources and incompatibles.

11. Toxicological Information

Toxicological Data:
Xylene: oral rat LD50: 4300 mg/kg; inhalation rat LC50: 5000 ppm/4H; skin rabbit LD50: > 1700 mg/kg; Irritation eye rabbit: 87 mg mild (Std. Draize); irritation skin rabbit 500 mg/24 moderate (Std. Draize); investigated as a tumorigen, mutagen, reproductive effector.
Ethyl benzene: oral rat LD50: 3500 mg/kg; skin rabbit LD50: 17800 uL/kg; investigated as a tumorigen, mutagen, reproductive effector.
Reproductive Toxicity:
May cause teratogenic effects.
  --------\Cancer Lists\------------------------------------------------------
                                         ---NTP Carcinogen---
  Ingredient                             Known    Anticipated    IARC Category
  ------------------------------------   -----    -----------    -------------
  m-Xylene (108-38-3)                     No          No              3
  o-Xylene (95-47-6)                      No          No              3
  p-Xylene (106-42-3)                     No          No              3
  Ethyl Benzene (100-41-4)                No          No             2B

12. Ecological Information

Environmental Fate:
Following data for xylene: When released into the soil, this material may evaporate to a moderate extent. When released into the soil, this material is expected to leach into groundwater. When released into the soil, this material may biodegrade to a moderate extent. When released into water, this material may evaporate to a moderate extent. When released into water, this material may biodegrade to a moderate extent. When released into the air, this material may be moderately degraded by reaction with photochemically produced hydroxyl radicals. When released into the air, this material is expected to have a half-life of less than 1 day. This material is not expected to significantly bioaccumulate. (mixed xylenes: octanol / water partition coefficient 3.1 - 3.2; bioconcentration factor = 1.3, eels)
Environmental Toxicity:
For xylene: This material is expected to be slightly toxic to aquatic life. The LC50/96-hour values for fish are between 10 and 100 mg/l.

13. Disposal Considerations

Whatever cannot be saved for recovery or recycling should be handled as hazardous waste and sent to a RCRA approved incinerator or disposed in a RCRA approved waste facility. Processing, use or contamination of this product may change the waste management options. State and local disposal regulations may differ from federal disposal regulations. Dispose of container and unused contents in accordance with federal, state and local requirements.

14. Transport Information

Domestic (Land, D.O.T.)
-----------------------
Proper Shipping Name: RQ, XYLENES
Hazard Class: 3
UN/NA: UN1307
Packing Group: III
Information reported for product/size: 398LB

International (Water, I.M.O.)
-----------------------------
Proper Shipping Name: XYLENES
Hazard Class: 3
UN/NA: UN1307
Packing Group: III
Information reported for product/size: 398LB


15. Regulatory Information

  --------\Chemical Inventory Status - Part 1\---------------------------------
  Ingredient                                       TSCA  EC   Japan  Australia
  -----------------------------------------------  ----  ---  -----  ---------
  m-Xylene (108-38-3)                               Yes  Yes   Yes      Yes                                      
  o-Xylene (95-47-6)                                Yes  Yes   Yes      Yes                                      
  p-Xylene (106-42-3)                               Yes  Yes   Yes      Yes                                      
  Ethyl Benzene (100-41-4)                          Yes  Yes   Yes      Yes                                      
 
  --------\Chemical Inventory Status - Part 2\---------------------------------
                                                          --Canada--
  Ingredient                                       Korea  DSL   NDSL  Phil.
  -----------------------------------------------  -----  ---   ----  -----
  m-Xylene (108-38-3)                               Yes   Yes   No     Yes
  o-Xylene (95-47-6)                                Yes   Yes   No     Yes
  p-Xylene (106-42-3)                               Yes   Yes   No     Yes
  Ethyl Benzene (100-41-4)                          Yes   Yes   No     Yes     
 
  --------\Federal, State & International Regulations - Part 1\----------------
                                             -SARA 302-    ------SARA 313------
  Ingredient                                 RQ    TPQ     List  Chemical Catg.
  -----------------------------------------  ---   -----   ----  --------------
  m-Xylene (108-38-3)                        No    No      Yes        No
  o-Xylene (95-47-6)                         No    No      Yes        No
  p-Xylene (106-42-3)                        No    No      Yes        No
  Ethyl Benzene (100-41-4)                   No    No      Yes        No
 
  --------\Federal, State & International Regulations - Part 2\----------------
                                                        -RCRA-    -TSCA-
  Ingredient                                 CERCLA     261.33     8(d) 
  -----------------------------------------  ------     ------    ------
  m-Xylene (108-38-3)                        1000       No         No                                                                  
  o-Xylene (95-47-6)                         1000       No         No                                                                 
  p-Xylene (106-42-3)                        100        No         Yes                                                                 
  Ethyl Benzene (100-41-4)                   1000       No         No   
 
 
Chemical Weapons Convention:  No     TSCA 12(b):  Yes    CDTA:  No
SARA 311/312:  Acute: Yes      Chronic: Yes  Fire: Yes Pressure: No
Reactivity: No          (Mixture / Liquid)
WARNING:
THIS PRODUCT CONTAINS A CHEMICAL(S) KNOWN TO THE STATE OF CALIFORNIA TO CAUSE CANCER.

Australian Hazchem Code: 3[Y]
Poison Schedule: None allocated.
WHMIS:
This MSDS has been prepared according to the hazard criteria of the Controlled Products Regulations (CPR) and the MSDS contains all of the information required by the CPR.

16. Other Information

NFPA Ratings: Health: 2 Flammability: 3 Reactivity: 0
Label Hazard Warning:
DANGER! HARMFUL OR FATAL IF SWALLOWED. VAPOR HARMFUL. AFFECTS CENTRAL NERVOUS SYSTEM. CAUSES SEVERE EYE IRRITATION. CAUSES IRRITATION TO SKIN AND RESPIRATORY TRACT. MAY BE HARMFUL IF ABSORBED THROUGH SKIN. CHRONIC EXPOSURE CAN CAUSE ADVERSE LIVER, KIDNEY, AND BLOOD EFFECTS. FLAMMABLE LIQUID AND VAPOR.
Label Precautions:
Keep away from heat, sparks and flame.
Avoid contact with eyes, skin and clothing.
Keep container closed.
Use only with adequate ventilation.
Avoid breathing vapor.
Wash thoroughly after handling.
Label First Aid:
Aspiration hazard. If swallowed, vomiting may occur spontaneously, but DO NOT INDUCE. If vomiting occurs, keep head below hips to prevent aspiration into lungs. Never give anything by mouth to an unconscious person. Call a physician immediately. If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. In case of contact, immediately flush eyes or skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. In all cases get medical attention immediately.
Product Use:
Laboratory Reagent.
Revision Information:
No Changes.
Disclaimer:
************************************************************************************************
Mallinckrodt Baker, Inc. provides the information contained herein in good faith but makes no representation as to its comprehensiveness or accuracy. This document is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. Individuals receiving the information must exercise their independent judgment in determining its appropriateness for a particular purpose. MALLINCKRODT BAKER, INC. MAKES NO REPRESENTATIONS OR WARRANTIES, EITHER EXPRESS OR IMPLIED, INCLUDING WITHOUT LIMITATION ANY WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE WITH RESPECT TO THE INFORMATION SET FORTH HEREIN OR THE PRODUCT TO WHICH THE INFORMATION REFERS. ACCORDINGLY, MALLINCKRODT BAKER, INC. WILL NOT BE RESPONSIBLE FOR DAMAGES RESULTING FROM USE OF OR RELIANCE UPON THIS INFORMATION.
************************************************************************************************
Prepared by: Environmental Health & Safety
Phone Number: (314) 654-1600 (U.S.A.)

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